منابع مشابه
Transgenerational Epigenetic Inheritance
Recent fi ndings in the emerging fi eld of transgenerational epigenetic inheritance suggest that the lifestyle choices and experiences of an individual have biological implications for offspring not yet conceived. Studies show that diet, drugs, and even social experiences can lead to life-long changes in gene expression. Some changes in gene expression are passed down to future generations. The...
متن کاملTransgenerational epigenetic inheritance
Marisa Bartolomei University of Pennsylvania, USA Stefan Beck University College London, UK Christoph Bock University of Vienna, AT Liran Carmel Hebrew University of Jerusalem, IL Katharina Gapp Sanger Institute, Cambridge, UK Johannes Graeff Ecole Polytechnique Fédérale, Lausanne, CH Carlos Guerrero-Bosagna Linköping University, SE Eva Jablonka Tel Aviv University, IL Josep Chillarón Hospital ...
متن کاملTransgenerational Epigenetic Inheritance in Animals
with abiotic and biotic components of their surroundings. Whereas many and perhaps most of the encounters pass with transient changes at the molecular and metabolic levels, some have a profound impact on the phenotypic appearance of an organism and, more importantly, on the phenotypic appearance of their progeny. Since genetic changes are rare and random in nature, their influence on species or...
متن کاملEpigenetic transgenerational inheritance of altered stress responses.
Ancestral environmental exposures have previously been shown to promote epigenetic transgenerational inheritance and influence all aspects of an individual's life history. In addition, proximate life events such as chronic stress have documented effects on the development of physiological, neural, and behavioral phenotypes in adulthood. We used a systems biology approach to investigate in male ...
متن کاملDevelopmental origins of epigenetic transgenerational inheritance
Environmental factors can induce epigenetic alterations in the germ cells that can potentially be transmitted transgenerationally. This non-genetic form of inheritance is termed epigenetic transgenerational inheritance and has been shown in a variety of species including plants, flies, worms, fish, rodents, pigs, and humans. This phenomenon operates during specific critical windows of exposure,...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2003
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(02)01377-5